Spray-drying is a method of drying liquid materials. This method is used to prepare granules or fine particles by spraying liquids and placing them next to a hot gas agent.

The spray drying process can be summarized in the following steps:

Spraying materials (in the form of slurry, solution, paste or suspension) to become droplets or fine particles.

The use of spray dryer or spray dryer technology in the process of drying pharmaceutical products with the aim of improving the quality of the manufactured product, has found wide application in laboratory research as well as in the field of industry. Spray dryer drying has been considered as a suitable method for drying heat-sensitive biological materials, such as enzymes and pharmaceutical proteins, with minimal loss of properties, improving the water solubility of the drug, and also in studies of pharmaceutical technology studies have been considered and used.

Today, this technology has found wide applications in the field of pharmaceutical and non-pharmaceutical and is used to prepare compounds of pills, vaccines, vitamins, blood products, enzymes, hormones, algae and yeast extract. By using spray drying method in the production of pharmaceutical products and due to the possibility of process control, a wide range of products with the required characteristics can be achieved.Drying by spray dryer is the continuous conversion of materials from liquid to dry particles by spraying into a hot drying chamber, which creates a sufficient volume of hot air to evaporate liquid droplets and dry the particles in this environment.

The liquid content can be a solution, suspension, emulsion, gel or paste as long as it can be pumped and sprayed. Despite the very high temperature of the drying chamber, the sprayed particles remain at a much lower temperature for a very short time due to moisture loss. Hence, this drying method is basically known as “low temperature drying”.The product obtained from the spray spray contains finer particles and better particle size distribution, appearance, texture, shedding characteristics, compressibility, bulk density, dispersibility and solubility.

One of the important applications of Spray Dryer is the production of ceramic powders and granules, although this method is also used in the production of detergents, food and pharmaceutical industries.